DIABETES MELLITUS
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Patients with DM are more affected by coronary artery disease and when treated by PCI with stent implantation they remain at higher risk of in-stent restenosis and adverse cardiovascular events
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The etiology of this failure is likely to be multifactorial such as diffuse disease progression, small vessel and endothelial dysfunction
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The presence of DM (particularly insulin-treated DM) has been a consistent, independent predictor of in-stent restenosis
ENVISOLUTION TECHNOLOGY
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Abluminal Coating
Facilitates mono directional drug release and less systemic exposure of drug leading to faster re-endothelialisation
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Fusion Coating
Coating on the stent and exposed parts of the balloon facilitate homogeneous drug delivery which addresses diused proliferative disease and focal restenosis
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Edge Coating
Additional 0.5 mm coating beyond the proximal and distal edge of the Stent addresses the edge restenosis
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Biodegradable film
The formation of circular film with biodegradable polymer facilitate maximum drug delivery in blood wet conditions